Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100177271Uncharacterized protein. (454 aa)    
Predicted Functional Partners:
F6SKP5_CIOIN
Uncharacterized protein; Belongs to the 5'-nucleotidase family.
    
  0.983
F7BJC2_CIOIN
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
  
 
 0.983
F7APS6_CIOIN
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.937
F6TT30_CIOIN
CTP_transf_like domain-containing protein.
    
 0.927
LOC100181174
Uncharacterized protein.
     
 0.923
LOC100183021
Cytosolic purine 5'-nucleotidase isoform X4.
   
 
 0.921
F6SLD6_CIOIN
Deacetylase sirtuin-type domain-containing protein.
   
 0.919
H2XWF2_CIOIN
NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
   
 0.919
LOC100185509
Cytosolic 5'-nucleotidase 1A.
    
 0.917
F6Q548_CIOIN
Uncharacterized protein.
     
 0.914
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (14%) [HD]