Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6V1Q0_CIOINUncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (895 aa)    
Predicted Functional Partners:
H2XSF3_CIOIN
Uncharacterized protein.
   
  
 0.527
LOC494392
Uncharacterized protein LOC494392.
   
  
 0.526
F6X5E1_CIOIN
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
  
 0.525
LOC100176457
Uncharacterized protein.
    
 
 0.499
F6WZV6_CIOIN
Cyclic nucleotide-binding domain-containing protein.
      
 0.492
H2XY07_CIOIN
Sodium/potassium-transporting ATPase subunit alpha.
    
 
 0.459
LOC100186976
Voltage-dependent calcium channel subunit alpha-2/delta-1.
   
 
 0.455
F6V0V9_CIOIN
Tudor domain-containing protein.
     
  0.453
F6WN97_CIOIN
Uncharacterized protein.
   
  
 0.428
F6S360_CIOIN
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
      
 0.421
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.