Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6UBQ5_CIOINCOMM domain-containing protein. (204 aa)    
Predicted Functional Partners:
LOC100175995
COMM domain-containing protein 2.
   
 0.992
F7B6D7_CIOIN
COMM domain-containing protein.
   
 0.990
F6ULS9_CIOIN
Uncharacterized protein.
    
 0.990
LOC100178405
COMM domain-containing protein.
   
 0.989
LOC100183378
COMM domain-containing protein 7-like.
   
 0.988
LOC100187497
Uncharacterized protein.
   
 0.988
F6SET0_CIOIN
COMM domain-containing protein.
   
 0.987
F6Y444_CIOIN
KOG2701 domain-containing protein.
    
 
 0.981
LOC100186572
Down syndrome critical region protein 3 homolog.
   
 
 0.972
LOC100176748
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.964
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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