Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6QQZ3_CIOINThioredoxin domain-containing protein. (202 aa)    
Predicted Functional Partners:
per-like
Peroxiredoxin-like.
   
   0.914
ciic3
Thioredoxin domain-containing protein 3 homolog; May be required during the final stages of sperm tail maturation. May act by reducing disulfide bonds within the sperm components (By similarity).
  
 0.868
F6WIH5_CIOIN
Sulfiredoxin.
   
 0.854
F6YRS8_CIOIN
Thioredoxin domain-containing protein.
  
 0.843
LOC100183957
Thioredoxin; Belongs to the thioredoxin family.
  
 0.820
LOC100181030
Thioredoxin; Belongs to the thioredoxin family.
  
 0.820
LOC100180659
Probable thioredoxin-2.
  
 0.803
H2Y0A0_CIOIN
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.785
gpx7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.763
F7BHL8_CIOIN
Uncharacterized protein.
  
 0.755
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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