Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6PUP9_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (708 aa)    
Predicted Functional Partners:
fz3/6
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.945
Cifrz
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.940
F6Q7C4_CIOIN
G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.939
Fz4
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.938
F6XLJ0_CIOIN
Uncharacterized protein.
  
  
 
0.902
F6Z4E6_CIOIN
Uncharacterized protein.
  
  
 
0.901
wnt5
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.747
F6U8A8_CIOIN
Vang-like protein.
    
 0.591
dsh
Dishevelled homolog.
    
 0.542
LOC778720
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.490
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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