Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100176009cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (367 aa)    
Predicted Functional Partners:
LOC100179599
Uncharacterized protein.
 
 
 0.998
LOC100179564
cAMP-dependent protein kinase type II regulatory subunit-like isoform X1.
 
 
 0.998
gsk
Glycogen synthase kinase Alpha/beta.
   
0.963
F6SE21_CIOIN
Uncharacterized protein.
  
0.941
F6RA92_CIOIN
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.935
Q69HQ2_CIOIN
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.932
LOC100186367
Gamma-aminobutyric acid receptor-associated protein.
   
 
 0.930
LOC100184788
Non-specific serine/threonine protein kinase.
  
 
0.929
F6V0V9_CIOIN
Tudor domain-containing protein.
    
 0.928
LOC100178444
Microtubule-associated proteins 1A/1B light chain 3B-like.
   
 
 0.927
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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