Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100178586Translocation protein SEC62-like isoform X2. (345 aa)    
Predicted Functional Partners:
LOC100179323
J domain-containing protein.
   
 0.999
LOC100175466
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 
 0.967
F6ZM86_CIOIN
Plug_translocon domain-containing protein.
   
 
 0.966
F6V299_CIOIN
Protein kinase domain-containing protein.
    
 
 0.958
LOC100178515
Probable signal peptidase complex subunit 2.
   
 
 0.930
sec61g
Protein transport protein Sec61 subunit gamma; Necessary for protein translocation in the endoplasmic reticulum.
   
 
 0.870
sec61g-2
Sec61 protein.
   
 
 0.870
F6W912_CIOIN
Protein kinase domain-containing protein.
    
 
 0.841
F6UET6_CIOIN
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
      
 0.838
LOC100186367
Gamma-aminobutyric acid receptor-associated protein.
   
 
 0.783
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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