Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100177402Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (336 aa)    
Predicted Functional Partners:
F6QAQ0_CIOIN
RabGGT_insert domain-containing protein.
   
 0.999
H2XMQ8_CIOIN
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.995
LOC100185850
Ras-related protein ORAB-1.
    
 0.949
LOC100176507
Synaptobrevin homolog YKT6-like isoform X2; Belongs to the synaptobrevin family.
    
 
 0.923
F6YIL9_CIOIN
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.877
F6Z156_CIOIN
Uncharacterized protein.
    
 0.834
LOC100185744
Protein tyrosine phosphatase type IVA 3.
    
 0.813
LOC100178332
Ras-related protein Rab-9B-like.
    
 0.800
COS41.2
Putative Ras-related protein Rab-33.
    
 0.783
LOC100182193
Ras-related protein Rab-5B.
    
 0.740
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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