Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pk1Uncharacterized protein. (1060 aa)    
Predicted Functional Partners:
dsh
Dishevelled homolog.
    
 0.999
F6U8A8_CIOIN
Vang-like protein.
    
 0.998
F6URP5_CIOIN
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
   
 0.849
LOC100177957
Tyrosine-protein kinase RYK.
   
  
 0.653
F6W446_CIOIN
E3 ubiquitin-protein ligase.
    
 0.643
fz3/6
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.628
LOC100184510
PCI domain-containing protein.
     
 0.612
rhoc
RhoA protein.
    
 0.610
F6XIV1_CIOIN
Uncharacterized protein.
      
 0.609
LOC100185096
26S proteasome regulatory subunit 7; Belongs to the AAA ATPase family.
     
  0.602
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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