Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F7B065_CIOINBestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (367 aa)    
Predicted Functional Partners:
LOC104265927
Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.
 
      0.770
F6U7K8_CIOIN
Uncharacterized protein.
      
 0.737
F6VUM2_CIOIN
Glutamine synthetase.
    
 
 0.638
LOC100181431
Uncharacterized protein.
      
 0.632
F6ZG25_CIOIN
Uncharacterized protein.
      
 0.545
F6QZW7_CIOIN
IRS-type PTB domain-containing protein.
      
 0.540
H2XW37_CIOIN
Uncharacterized protein.
   
  
 0.520
LOC100181945
Tetraspanin-13; Belongs to the tetraspanin (TM4SF) family.
      
 0.513
H2XT62_CIOIN
BTB domain-containing protein.
      
 0.511
LOC100181904
Rhomboid protein 1, mitochondrial.
      
 0.510
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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