Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nfkbp105Uncharacterized protein. (1202 aa)    
Predicted Functional Partners:
Q4H3C1_CIOIN
IkappaB kinase.
   
 0.993
rel1
Rel1 protein isoform X1.
   
 0.987
F6R7T5_CIOIN
Uncharacterized protein.
    
 0.939
LOC100182077
TNFAIP3-interacting protein 1 isoform X2.
   
 
 0.926
Ikappab
ANK_REP_REGION domain-containing protein.
   
 0.847
betaTrCP
Beta-transducin repeat-containing HOMOLOGUE protein.
    
 0.775
Cibeta-catenin
Uncharacterized protein.
    
 0.759
F6TZA7_CIOIN
Uncharacterized protein.
    
 0.759
Q1RPY5_CIOIN
Zinc finger protein.
   
 0.755
E2f4/5
E2F_TDP domain-containing protein.
    
 
 0.677
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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