Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6VN25_CIOINUncharacterized protein. (889 aa)    
Predicted Functional Partners:
F6Z8G0_CIOIN
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.996
LOC100182514
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.980
F6YH93_CIOIN
Uncharacterized protein.
   
 0.978
LOC113474468
Replication protein A 14 kDa subunit-like.
    
 0.975
H2XVZ6_CIOIN
Uncharacterized protein.
   
 
 0.966
F6WCV2_CIOIN
Protein kinase domain-containing protein.
   
 0.959
H2Y306_CIOIN
Sld5 domain-containing protein.
   
 
 0.954
F6QND3_CIOIN
Mcm10 domain-containing protein.
   
 
 0.941
F6UIT3_CIOIN
Uncharacterized protein.
   
 0.934
F6PLC9_CIOIN
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 0.934
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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