Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100180059Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (626 aa)    
Predicted Functional Partners:
LOC100185024
Spermatogenesis-defective protein 39 homolog.
   
 
 0.992
F6PRZ9_CIOIN
Vps8 domain-containing protein.
    
 0.980
F6SZ37_CIOIN
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
   
 0.970
LOC100186755
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
  
0.958
LOC100185122
Uncharacterized protein.
   
 0.948
F6Q2U2_CIOIN
CNH domain-containing protein.
   
 0.941
zf(ring)-20
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
   
 0.904
F7BBV8_CIOIN
CNH domain-containing protein.
   
 0.870
LOC100178332
Ras-related protein Rab-9B-like.
    
 
 0.844
H2Y130_CIOIN
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.841
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (20%) [HD]