Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tsc22Uncharacterized protein. (746 aa)    
Predicted Functional Partners:
Raf1
Uncharacterized protein.
    
 0.915
F7BGT4_CIOIN
E3 ubiquitin-protein ligase.
    
 0.870
F6ZIT4_CIOIN
Protein kinase domain-containing protein.
    
 
 0.796
H2XK39_CIOIN
Protein kinase domain-containing protein.
    
  0.537
F6ZFM9_CIOIN
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.535
LOC100182808
AGC-kinase C-terminal domain-containing protein.
    
 0.535
LOC100176760
Proteasome subunit alpha type.
    
 
 0.505
F7A6C5_CIOIN
ANK_REP_REGION domain-containing protein.
      
 0.501
LOC100185384
ubiquitin-60S ribosomal protein L40.
     
  0.408
F6WQL4_CIOIN
BZIP domain-containing protein.
   
  
 0.404
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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