Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100176643Uncharacterized protein. (476 aa)    
Predicted Functional Partners:
LOC100175543
Lathosterol oxidase-like; Belongs to the sterol desaturase family.
   
 0.995
LOC100181233
Delta(24)-sterol reductase-like.
 
 
 0.993
F6ZXA7_CIOIN
FAD-binding PCMH-type domain-containing protein.
   
 0.981
F6UDM9_CIOIN
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
     
 0.903
H2XR44_CIOIN
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
     
 0.903
F6Z833_CIOIN
Uncharacterized protein.
   
 
 0.883
F6RFK8_CIOIN
Methyltransf_11 domain-containing protein.
   
 
 0.878
LOC100180521
3-keto-steroid reductase-like.
   
 
 0.876
LOC100175295
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.812
F6SSS9_CIOIN
Nudix hydrolase domain-containing protein.
   
  
 0.804
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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