Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100178496CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family. (294 aa)    
Predicted Functional Partners:
LOC100181511
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
   
 0.919
F7BMH5_CIOIN
UBX domain-containing protein.
   
 0.906
LOC100176246
Ubiquitin-like domain-containing protein.
    
 0.894
LOC100182516
RING-box protein 1.
    
 0.840
LOC100177815
elongin-C-like; Belongs to the SKP1 family.
   
 0.830
F6Z3T2_CIOIN
TIP120 domain-containing protein.
   
 0.795
F6UG35_CIOIN
Uncharacterized protein.
   
 0.791
Zf(cxxc)-1
Uncharacterized protein.
    
 0.783
Zf(cxxc)-4
Uncharacterized protein.
    
 0.783
H2XR56_CIOIN
JmjC domain-containing protein.
    
 0.783
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (18%) [HD]