Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6Z3T2_CIOINTIP120 domain-containing protein. (1277 aa)    
Predicted Functional Partners:
F6PW28_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.998
LOC100182516
RING-box protein 1.
    
 0.989
LOC100183130
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.988
F6R472_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.983
F6PKZ6_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.979
LOC100175879
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.972
H2XUY6_CIOIN
Cullin_Nedd8 domain-containing protein; Belongs to the cullin family.
   
 0.941
F6PKS9_CIOIN
Cullin domain-containing protein; Belongs to the cullin family.
   
 0.931
LOC100181511
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.925
F7ANR5_CIOIN
CPSF_A domain-containing protein.
   
 0.889
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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