Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
F6XWE7_CIOINSerine/threonine-protein kinase PLK. (754 aa)    
Predicted Functional Partners:
F7B1X4_CIOIN
WD_REPEATS_REGION domain-containing protein.
   
 0.947
H2XWH9_CIOIN
Protein kinase domain-containing protein.
   
 0.933
LOC100187303
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.913
F6TJJ7_CIOIN
Uncharacterized protein.
  
  
 
0.905
F7AQS5_CIOIN
Peptidase C50 domain-containing protein.
   
 0.889
H2XKH3_CIOIN
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.888
F7A0P0_CIOIN
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.866
F6UNP2_CIOIN
WD_REPEATS_REGION domain-containing protein.
   
 0.865
LOC100180856
Rad21_Rec8 domain-containing protein.
   
 0.855
H2XRK6_CIOIN
HORMA domain-containing protein.
   
 0.854
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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