Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
LOC100177347NEDD8-conjugating enzyme Ubc12-like; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)    
Predicted Functional Partners:
LOC100176246
Ubiquitin-like domain-containing protein.
   
 0.958
LOC100183602
E2_bind domain-containing protein.
    
 0.939
LOC100182516
RING-box protein 1.
   
 0.935
LOC100180811
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
    
 0.930
LOC100185177
NEDD8-activating enzyme E1 regulatory subunit.
    
 0.911
F6PW28_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.897
F6PKZ6_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.846
F6Z8N3_CIOIN
ThiF domain-containing protein.
    
 0.843
LOC100186269
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
    
 0.838
LOC100176463
UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.
    
 0.836
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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