Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6WI66_CIOINUncharacterized protein; Belongs to the DEAD box helicase family. (659 aa)    
Predicted Functional Partners:
F7B4V3_CIOIN
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
   
 0.791
LOC100175824
116 kDa U5 small nuclear ribonucleoprotein component.
   
 0.763
LOC100176856
Uncharacterized protein.
   
 0.762
LOC100182767
Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.
   
 
 0.742
LOC100177133
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.738
H2Y0Q6_CIOIN
Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.
   
 
 0.735
F6RE18_CIOIN
ATP synthase subunit gamma.
   
 
 0.724
F7B898_CIOIN
Uncharacterized protein; Belongs to the DEAD box helicase family.
  
 
0.723
LOC100177596
Eukaryotic initiation factor 4A-I; Belongs to the DEAD box helicase family.
  
 
0.713
F6W453_CIOIN
Uncharacterized protein.
    
  0.712
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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