Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100183329ULP_PROTEASE domain-containing protein. (387 aa)    
Predicted Functional Partners:
LOC100178367
Small ubiquitin-related modifier.
   
 0.974
F6PI87_CIOIN
ULP_PROTEASE domain-containing protein.
   
 0.973
F6RKQ2_CIOIN
Uncharacterized protein.
   
 
 0.927
F6W9U2_CIOIN
Rad60-SLD domain-containing protein.
   
 0.899
H2XM91_CIOIN
SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.
    
 
 0.844
H2XMB6_CIOIN
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.843
pias
Uncharacterized protein.
    
 
 0.771
pias-like
Zinc finger protein.
    
 
 0.737
Ci-htf-1
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 
 0.725
F6PK54_CIOIN
Uncharacterized protein.
    
 
 0.722
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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