Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100183094Ras-related protein rab7-like. (206 aa)    
Predicted Functional Partners:
LOC100181521
Pleckstrin homology domain-containing family M member 1-like isoform X1.
    
 0.994
H2XMQ8_CIOIN
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.989
H2XPJ6_CIOIN
Uncharacterized protein.
   
 0.989
H2XRD9_CIOIN
Rab-GAP TBC domain-containing protein.
    
 0.983
F6ZS04_CIOIN
Uncharacterized protein.
   
 0.976
F6YU56_CIOIN
Uncharacterized protein.
    
 0.964
LOC100176748
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.961
H2XXJ8_CIOIN
Uncharacterized protein.
    
 0.960
LOC100185122
Uncharacterized protein.
    
 0.954
F6Q2U2_CIOIN
CNH domain-containing protein.
    
 0.954
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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