Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100176463UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1036 aa)    
Predicted Functional Partners:
r27a
R27a protein isoform X1.
   
 0.990
LOC100175224
Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.985
LOC100184240
Ubiquitin-conjugating enzyme E2 35-like isoform X2; Belongs to the ubiquitin-conjugating enzyme family.
  
 0.984
LOC100176571
Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.980
F6XWG9_CIOIN
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.963
F6PKV2_CIOIN
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.959
LOC100186965
Ubiquitin-conjugating enzyme E2 L3-like isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
  
 0.956
LOC100185384
ubiquitin-60S ribosomal protein L40.
   
 0.956
H2XUW4_CIOIN
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.951
LOC100177184
Ubiquitin-conjugating enzyme E2 W-like.
   
 0.950
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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