Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100181475GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (300 aa)    
Predicted Functional Partners:
F6S9L7_CIOIN
Uncharacterized protein.
    
 
 0.992
H2XVC3_CIOIN
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
    
 
 0.987
F6QR00_CIOIN
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.976
LOC100181341
DNA-directed RNA polymerase II subunit RPB11-a isoform X1.
    
 
 0.908
F7BP59_CIOIN
Uncharacterized protein.
    
 
 0.882
LOC100180720
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
   
 
 0.853
F6Y5Q3_CIOIN
RPOLD domain-containing protein.
    
 
 0.814
H2XZ54_CIOIN
RPOLD domain-containing protein.
    
 
 0.814
LOC100179207
uroporphyrinogen-III synthase-like.
      
 0.742
F6ZGM2_CIOIN
Iwr1 domain-containing protein.
    
 
 0.645
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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