Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6VH72_CIOINCS domain-containing protein. (441 aa)    
Predicted Functional Partners:
F6U2M6_CIOIN
PUA domain-containing protein.
   
 0.999
LOC100181113
H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
   
 
 0.968
LOC100183367
RuvB-like helicase; Belongs to the RuvB family.
   
 
 0.887
LOC100177411
RuvB-like helicase; Belongs to the RuvB family.
    
 
 0.879
H2XP61_CIOIN
H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
   
 
 0.828
F6WN37_CIOIN
Uncharacterized protein.
   
 0.751
F6UT38_CIOIN
Uncharacterized protein.
      
 0.700
F6U609_CIOIN
Nop domain-containing protein.
   
  
 0.695
H2XT24_CIOIN
Uncharacterized protein.
   
  
 0.688
F6R982_CIOIN
WD_REPEATS_REGION domain-containing protein.
      
 0.674
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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