Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100178673Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)    
Predicted Functional Partners:
LOC100186457
Glyceraldehyde-3-phosphate dehydrogenase.
  
 0.997
LOC100183090
Triosephosphate isomerase.
  
 0.995
F6PZE7_CIOIN
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
  
 0.991
F7A429_CIOIN
Transket_pyr domain-containing protein.
  
 0.979
F7AZD3_CIOIN
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 0.966
LOC100177203
Alpha-enolase-like.
   
 0.964
LOC100176649
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.952
F6UI47_CIOIN
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.939
F6V8G3_CIOIN
Enolase_C domain-containing protein.
   
 0.931
F7BN93_CIOIN
PfkB domain-containing protein.
   
 
 0.930
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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