Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
F7B3P4_CIOINUncharacterized protein. (325 aa)    
Predicted Functional Partners:
LOC100181653
PAW domain-containing protein.
    
 0.997
LOC100182082
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.995
F6QS20_CIOIN
VWFA domain-containing protein.
   
 0.984
LOC100179498
DNA repair protein complementing XP-A cells homolog.
    
 0.974
LOC100179683
26S proteasome non-ATPase regulatory subunit 14.
   
 0.972
F6XKP0_CIOIN
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.971
F6UXR3_CIOIN
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 0.962
LOC100185384
ubiquitin-60S ribosomal protein L40.
   
 0.962
F6SDU1_CIOIN
PCI domain-containing protein.
   
 0.961
LOC100186374
26S proteasome non-ATPase regulatory subunit 11.
   
 0.959
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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