STRINGSTRING
ci-htf-1 protein (Ciona intestinalis) - STRING interaction network
"ci-htf-1" - Transcription factor in Ciona intestinalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ci-htf-1Transcription factor ; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1297 aa)    
Predicted Functional Partners:
ENSCING00000009221
Uncharacterized protein (572 aa)
     
  0.992
ENSCING00000025028
Uncharacterized protein (231 aa)
     
   
  0.989
ENSCING00000005985
Uncharacterized protein ; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (1233 aa)
     
   
  0.989
ENSCING00000003086
Uncharacterized protein (504 aa)
     
 
  0.985
ENSCING00000004923
Uncharacterized protein (234 aa)
     
 
  0.970
ENSCING00000014118
Proliferating cell nuclear antigen ; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (262 aa)
   
  0.969
supt16h
Uncharacterized protein (1035 aa)
     
  0.969
ssrp1
FACT complex subunit SSRP1 ; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] (603 aa)
     
 
  0.962
ENSCING00000003660
Structural maintenance of chromosomes protein (1253 aa)
     
 
  0.960
ENSCING00000021036
Uncharacterized protein (549 aa)
   
  0.959
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
Server load: low (6%) [HD]