Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC100184965Aspartate aminotransferase. (415 aa)    
Predicted Functional Partners:
LOC100178529
Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.
   
 0.991
LOC100179315
Aspartate aminotransferase.
  
 
0.986
F7AQA9_CIOIN
Aminotran_1_2 domain-containing protein.
   
 0.985
H2Y3K9_CIOIN
Malate dehydrogenase.
   
 0.984
LOC100174998
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.982
F6S7U7_CIOIN
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.982
F6XHC0_CIOIN
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.974
LOC100183684
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 
 0.971
F6Z761_CIOIN
Uncharacterized protein.
   
 0.958
LOC100185199
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.953
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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