Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100176285Uncharacterized protein. (318 aa)    
Predicted Functional Partners:
LOC100185650
Phosphoglucomutase-2.
  
 
 0.970
F7A429_CIOIN
Transket_pyr domain-containing protein.
  
 0.944
LOC100176649
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.940
F6ZG04_CIOIN
PfkB domain-containing protein.
    
 0.937
LOC100178673
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
   
 
 0.907
LOC100182755
Aldehyde dehydrogenase family 16 member A1-like; Belongs to the aldehyde dehydrogenase family.
 0.905
LOC100183090
Triosephosphate isomerase.
  
 0.899
F7AZD3_CIOIN
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.880
LOC100186457
Glyceraldehyde-3-phosphate dehydrogenase.
    
 0.869
F6UI47_CIOIN
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.857
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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