Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6ZZ40_CIOINUncharacterized protein. (4467 aa)    
Predicted Functional Partners:
F6UM48_CIOIN
Uncharacterized protein.
    
   0.553
F7B690_CIOIN
CAP-Gly domain-containing protein.
   
 0.549
LOC100180225
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.
   
 0.526
F6UI30_CIOIN
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
   
 0.514
F7BML6_CIOIN
WD_REPEATS_REGION domain-containing protein.
    
 0.505
LOC100181072
Microtubule-associated protein RP/EB family member 1 isoform X4.
    
 0.479
ciic3
Thioredoxin domain-containing protein 3 homolog; May be required during the final stages of sperm tail maturation. May act by reducing disulfide bonds within the sperm components (By similarity).
    
 
 0.462
dynll6
Dynein light chain.
    
 0.448
F7APT3_CIOIN
Uncharacterized protein.
    
 0.416
LOC100185458
Uncharacterized protein LOC100185458.
    
 0.414
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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