Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6WCT6_CIOINPDZ domain-containing protein. (347 aa)    
Predicted Functional Partners:
LOC445704
TC10 protein.
    
 0.750
LOC100180817
PHB domain-containing protein.
      
 0.585
F7AQ56_CIOIN
Uncharacterized protein.
      
 0.584
LOC100175118
Na(+)/H(+) exchange regulatory cofactor NHE-RF1.
      
 0.567
F6S6P6_CIOIN
Uncharacterized protein.
      
 0.567
F6W2N4_CIOIN
Uncharacterized protein.
    
 0.548
F6R9A6_CIOIN
Uncharacterized protein.
    
 0.548
H2XJZ0_CIOIN
Guanylate kinase-like domain-containing protein.
    
 0.548
LOC100182780
Ras-related protein Rab-3.
    
 0.547
cagf9
HMG box domain-containing protein.
    
 
 0.520
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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