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aptx protein (Ciona intestinalis) - STRING interaction network
"aptx" - Aprataxin in Ciona intestinalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptxAprataxin ; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non- ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5’-phosphate termini, resulting in the production of 5’-phosphate termini that can be efficiently rejoined (By similarity) (380 aa)    
Predicted Functional Partners:
ENSCING00000020135
Uncharacterized protein (480 aa)
       
 
  0.590
ENSCING00000019424
Uncharacterized protein (110 aa)
     
  0.574
Cin.27869
Uncharacterized protein (246 aa)
     
  0.574
ENSCING00000022190
Uncharacterized protein (326 aa)
     
  0.568
ENSCING00000013269
Uncharacterized protein (154 aa)
     
   
  0.517
ENSCING00000005638
Uncharacterized protein (217 aa)
     
  0.507
ENSCING00000013953
Uncharacterized protein (219 aa)
           
  0.495
ENSCING00000009513
Lysyl-tRNA synthetase (576 aa)
           
  0.477
smu1
Uncharacterized protein (513 aa)
     
   
  0.472
ENSCING00000022588
Uncharacterized protein (112 aa)
     
 
  0.462
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
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