Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100181883AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1057 aa)    
Predicted Functional Partners:
LOC100180975
AP-3 complex subunit sigma-2 isoform X1.
   
 0.997
LOC100179714
AP-3 complex subunit mu-1-like; Belongs to the adaptor complexes medium subunit family.
   
 0.996
F6T2R5_CIOIN
AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family.
   
 0.993
F6T2N7_CIOIN
Adaptin_N domain-containing protein.
   
 0.956
LOC100176522
AP-1 complex subunit gamma.
   
 0.904
LOC100175300
AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
   
 
 0.859
LOC100179571
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 
 0.786
H2XZK4_CIOIN
B2-adapt-app_C domain-containing protein.
 
 
 0.786
LOC104265915
Adaptin_N domain-containing protein.
   
 0.775
F7AMF6_CIOIN
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.697
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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