Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
F6PKT6_CIOINRNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (822 aa)    
Predicted Functional Partners:
LOC100177272
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.992
LOC100177778
DNA-directed RNA polymerase II subunit RPB7.
    
 0.991
F6X618_CIOIN
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.987
F6QR00_CIOIN
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.984
LOC100179943
General transcription factor IIF subunit 2.
    
 0.983
LOC100181821
Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.
    
 0.963
LOC100182343
Transcription initiation factor IIB-like.
    
 
 0.955
LOC100183293
Transcription elongation factor A protein 1.
   
 0.951
F6XIG6_CIOIN
RPOL4c domain-containing protein.
    
 0.951
LOC100178802
Transcription elongation factor SPT5.
    
 0.930
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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