Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Socs6Uncharacterized protein. (406 aa)    
Predicted Functional Partners:
LOC100177815
elongin-C-like; Belongs to the SKP1 family.
    
 0.971
F6PKZ6_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.967
F6PKS9_CIOIN
Cullin domain-containing protein; Belongs to the cullin family.
   
 0.875
stat-b
Signal transducer and activator of transcription.
    
 0.650
F6PPL2_CIOIN
Uncharacterized protein.
    
 0.650
F6W673_CIOIN
RBR-type E3 ubiquitin transferase.
    
   0.628
F6Z3T2_CIOIN
TIP120 domain-containing protein.
     
 0.609
LOC100176246
Ubiquitin-like domain-containing protein.
     
 0.582
LOC100183130
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.575
LOC100186269
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
   
 
  0.523
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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