Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6R6J0_CIOINUncharacterized protein. (585 aa)    
Predicted Functional Partners:
LOC100183146
Uncharacterized protein.
   
 0.999
LOC100178867
Mitochondrial import receptor subunit TOM40 homolog isoform X1.
   
 0.998
H2XY09_CIOIN
Uncharacterized protein.
   
 0.996
F6W141_CIOIN
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
   
 0.966
H2XR40_CIOIN
RING-type domain-containing protein.
     
 0.959
F6VDC4_CIOIN
Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
     
 0.956
F6VHL9_CIOIN
RING-CH-type domain-containing protein.
    
 0.951
LOC100176189
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
     
 0.905
F6W9U8_CIOIN
PB1 domain-containing protein.
     
 0.904
F6ZA91_CIOIN
Uncharacterized protein.
   
  0.904
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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