STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100181968TP_methylase domain-containing protein. (285 aa)    
Predicted Functional Partners:
F6VZF6_CIOIN
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.
   
 0.890
LOC100181314
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2.
   
 0.887
F6XKZ0_CIOIN
EFG_C domain-containing protein.
    
 0.719
F6XKY1_CIOIN
Tr-type G domain-containing protein.
    
 0.719
F6XKX5_CIOIN
GTP_EFTU_D2 domain-containing protein.
    
 0.719
LOC100176897
Uncharacterized protein.
   
  
 0.686
F6TGX7_CIOIN
Uncharacterized protein.
   
  
 0.683
F6WYJ4_CIOIN
Tr-type G domain-containing protein.
    
 0.676
F6WQI3_CIOIN
S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.
   
  
 0.644
F6YUN5_CIOIN
WD_REPEATS_REGION domain-containing protein.
      
 0.642
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (30%) [HD]