STRINGSTRING
LOC778622 protein (Ciona intestinalis) - STRING interaction network
"LOC778622" - Fringe in Ciona intestinalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC778622Fringe (381 aa)    
Predicted Functional Partners:
n
Notch precursor (2549 aa)
     
  0.965
jagged
Uncharacterized protein ; Putative Notch ligand involved in the mediation of Notch signaling (1043 aa)
     
 
  0.727
ENSCING00000004569
Uncharacterized protein (938 aa)
     
 
  0.614
lhx2/9
Uncharacterized protein (171 aa)
       
 
  0.610
ENSCING00000007101
Uncharacterized protein (608 aa)
     
 
  0.572
delta
Delta protein ; Putative Notch ligand involved in the mediation of Notch signaling (706 aa)
       
 
  0.528
irx-b
Transcription factor protein (570 aa)
     
 
  0.522
ENSCING00000012537
Uncharacterized protein (570 aa)
     
 
  0.522
irx-c
Transcription factor protein (697 aa)
     
 
  0.522
su(h)
Suppressor of hairless homolog ; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity). Required for the transcriptional expression of Brachyury, suggesting that it participates in notochord differentiation (554 aa)
           
  0.511
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
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