Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
JnkMitogen-activated protein kinase. (437 aa)    
Predicted Functional Partners:
Mapkk7
Protein kinase domain-containing protein.
  
 
0.999
Mapkk4
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
0.999
jun
Transcription factor protein.
   
 0.999
F6Y6H6_CIOIN
BZIP domain-containing protein.
   
 0.985
Foxo
Fork-head domain-containing protein.
    
 0.976
fos
Transcription factor protein.
   
 0.975
LOC100180686
C-Jun-amino-terminal kinase-interacting protein 1 isoform X2.
   
 
 0.972
LOC448957
Rac4 protein.
    
 0.961
Rac3a
Uncharacterized protein.
    
 0.961
LOC448958
Rac5 protein.
    
 0.961
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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