Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100180018Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa)    
Predicted Functional Partners:
F6SUM0_CIOIN
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.977
F7AAH8_CIOIN
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.977
H2XU13_CIOIN
Citrate synthase; Belongs to the citrate synthase family.
  
 0.908
F6WXA3_CIOIN
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.901
F6UET6_CIOIN
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.881
F6UHA9_CIOIN
2-oxogl_dehyd_N domain-containing protein.
   
 0.881
LOC100178529
Malate dehydrogenase, mitochondrial-like; Belongs to the LDH/MDH superfamily.
  
 0.877
LOC100181512
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.875
F6SUS9_CIOIN
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.869
LOC100184016
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 0.863
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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