STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100180099Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (214 aa)    
Predicted Functional Partners:
F6XWY9_CIOIN
TPR_REGION domain-containing protein.
    
 0.994
F6YDG1_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.973
LOC100182501
TPR_REGION domain-containing protein.
    
 0.963
LOC100176838
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
   
 0.946
F6ZE60_CIOIN
ANAPC4 domain-containing protein.
    
 0.945
F6PKV2_CIOIN
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.934
F6SSU2_CIOIN
TPR_REGION domain-containing protein.
    
 0.930
F7B1X4_CIOIN
WD_REPEATS_REGION domain-containing protein.
   
 0.921
F6UNB7_CIOIN
ANAPC5 domain-containing protein.
    
 0.921
F6XGY9_CIOIN
Uncharacterized protein.
    
 0.919
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.