Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
F6XHT6_CIOINUvrD-like helicase C-terminal domain-containing protein. (212 aa)    
Predicted Functional Partners:
F6PW28_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 
 0.920
F6QXW9_CIOIN
Helicase ATP-binding domain-containing protein.
    
 
 0.865
F6UAB2_CIOIN
FANCM-MHF_bd domain-containing protein.
    
 
 0.865
H2XN42_CIOIN
Uncharacterized protein.
    
 
 0.865
LOC100181925
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.
  
 
 0.863
LOC100184693
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.846
LOC100182516
RING-box protein 1.
    
 
 0.803
LOC100179894
Werner syndrome ATP-dependent helicase homolog isoform X1.
  
 
 0.793
H2XKT2_CIOIN
3'-5' exonuclease domain-containing protein.
  
 
 0.793
LOC100181511
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 
 0.788
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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