STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6W0C3_CIOINUncharacterized protein. (683 aa)    
Predicted Functional Partners:
H2XSN3_CIOIN
Pyruvate carboxyltransferase domain-containing protein.
 
 
 0.971
LOC100177845
acetyl-CoA acetyltransferase, mitochondrial-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.968
LOC100187496
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial-like.
  
 
 0.956
LOC100180564
Peroxisomal bifunctional enzyme-like isoform X1.
  
 
 0.939
LOC100182913
Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.939
LOC100175295
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.929
LOC100180566
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.928
LOC100183445
3-hydroxybutyrate dehydrogenase type 2-like.
    
 0.919
F6RYU3_CIOIN
Uncharacterized protein.
     
 0.908
H2XU13_CIOIN
Citrate synthase; Belongs to the citrate synthase family.
  
 0.846
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.