node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F6Q1G7_CIOIN | F6RN60_CIOIN | ENSCINP00000001368 | ENSCINP00000023900 | AAA domain-containing protein; Belongs to the AAA ATPase family. | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | 0.580 |
F6Q1G7_CIOIN | LOC100181871 | ENSCINP00000001368 | ENSCINP00000005346 | AAA domain-containing protein; Belongs to the AAA ATPase family. | t-SNARE coiled-coil homology domain-containing protein. | 0.439 |
F6RN60_CIOIN | F6Q1G7_CIOIN | ENSCINP00000023900 | ENSCINP00000001368 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.580 |
F6RN60_CIOIN | F6TDQ4_CIOIN | ENSCINP00000023900 | ENSCINP00000025635 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Ubiquitin-like domain-containing protein. | 0.695 |
F6RN60_CIOIN | F6VKW3_CIOIN | ENSCINP00000023900 | ENSCINP00000014826 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Uncharacterized protein. | 0.991 |
F6RN60_CIOIN | F6ZM86_CIOIN | ENSCINP00000023900 | ENSCINP00000018963 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Plug_translocon domain-containing protein. | 0.661 |
F6RN60_CIOIN | F7B3P4_CIOIN | ENSCINP00000023900 | ENSCINP00000017031 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Uncharacterized protein. | 0.910 |
F6RN60_CIOIN | H2XJV8_CIOIN | ENSCINP00000023900 | ENSCINP00000029940 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Uncharacterized protein. | 0.993 |
F6RN60_CIOIN | LOC100175466 | ENSCINP00000023900 | ENSCINP00000029828 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | 0.596 |
F6RN60_CIOIN | LOC100176246 | ENSCINP00000023900 | ENSCINP00000006091 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Ubiquitin-like domain-containing protein. | 0.559 |
F6RN60_CIOIN | LOC100181871 | ENSCINP00000023900 | ENSCINP00000005346 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | t-SNARE coiled-coil homology domain-containing protein. | 0.752 |
F6RN60_CIOIN | SRP54 | ENSCINP00000023900 | ENSCINP00000015156 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.624 |
F6TDQ4_CIOIN | F6RN60_CIOIN | ENSCINP00000025635 | ENSCINP00000023900 | Ubiquitin-like domain-containing protein. | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | 0.695 |
F6TDQ4_CIOIN | F6VKW3_CIOIN | ENSCINP00000025635 | ENSCINP00000014826 | Ubiquitin-like domain-containing protein. | Uncharacterized protein. | 0.982 |
F6VKW3_CIOIN | F6RN60_CIOIN | ENSCINP00000014826 | ENSCINP00000023900 | Uncharacterized protein. | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | 0.991 |
F6VKW3_CIOIN | F6TDQ4_CIOIN | ENSCINP00000014826 | ENSCINP00000025635 | Uncharacterized protein. | Ubiquitin-like domain-containing protein. | 0.982 |
F6VKW3_CIOIN | F7B3P4_CIOIN | ENSCINP00000014826 | ENSCINP00000017031 | Uncharacterized protein. | Uncharacterized protein. | 0.862 |
F6VKW3_CIOIN | H2XJV8_CIOIN | ENSCINP00000014826 | ENSCINP00000029940 | Uncharacterized protein. | Uncharacterized protein. | 0.679 |
F6VKW3_CIOIN | LOC100175466 | ENSCINP00000014826 | ENSCINP00000029828 | Uncharacterized protein. | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | 0.541 |
F6VKW3_CIOIN | LOC100176246 | ENSCINP00000014826 | ENSCINP00000006091 | Uncharacterized protein. | Ubiquitin-like domain-containing protein. | 0.486 |