STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6YYA5_CIOINtRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (251 aa)    
Predicted Functional Partners:
H2Y1I5_CIOIN
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
 
      0.712
LOC100185889
Uncharacterized protein.
    
 
 0.671
LOC100180887
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
  
 0.547
F6WW70_CIOIN
Uncharacterized protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
   
  
 0.544
LOC100178583
Tyrosine--tRNA ligase.
     
 0.530
F6SV73_CIOIN
SAM-dependent MTase TRM10-type domain-containing protein.
   
  
 0.528
F6UDW5_CIOIN
Protein kinase domain-containing protein.
 
      0.519
F7BA39_CIOIN
Uncharacterized protein.
     
 0.481
F7B7E9_CIOIN
tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.480
soxh
HMG box domain-containing protein.
      
 0.480
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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