STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2XW81_CIOINAB hydrolase-1 domain-containing protein. (275 aa)    
Predicted Functional Partners:
F6ZFG0_CIOIN
AB hydrolase-1 domain-containing protein.
  
 
 0.754
F6PJS6_CIOIN
AB hydrolase-1 domain-containing protein.
  
 
 0.754
F6UET6_CIOIN
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.733
LOC100178002
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
      
 0.617
LOC100181032
SCP2 domain-containing protein.
  
 0.608
LOC100176285
Uncharacterized protein.
  
 0.554
LOC100182764
Charged multivesicular body protein 5.
 
  
   0.544
F6UTV1_CIOIN
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 
 0.531
LOC100186144
Fe-ADH domain-containing protein.
  
 0.526
F6Z7L9_CIOIN
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.513
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (14%) [HD]