STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2XXR3_CIOINPoly [ADP-ribose] polymerase. (472 aa)    
Predicted Functional Partners:
Ci-ZF(PARP)-3
Zinc finger protein.
 
     
0.875
LOC100177850
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
 0.759
H2XW90_CIOIN
Uncharacterized protein.
  
 
 0.739
LOC100177452
Uncharacterized protein.
   
 
 0.705
LOC100183893
Uncharacterized protein.
   
 
 0.703
LOC100175865
Histone PARylation factor 1.
   
 
 0.701
zf(c2h2)-102
ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.
   
 
 0.695
F6QM85_CIOIN
Uncharacterized protein.
    
 0.660
F6YH93_CIOIN
Uncharacterized protein.
   
 
 0.650
F6ZQY6_CIOIN
Poly [ADP-ribose] polymerase.
  
0.642
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.