STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2Y1J5_CIOINUncharacterized protein. (448 aa)    
Predicted Functional Partners:
F7B898_CIOIN
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.950
F7B4V3_CIOIN
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
    
 
 0.934
LOC100180168
Protein LSM14 homolog A-B isoform X1.
   
 
 0.919
F7BBD1_CIOIN
Uncharacterized protein.
   
 
 0.660
LOC101242392
Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family.
   
 
 0.618
Rbp1-like
ARID domain-containing protein.
    
 0.581
LOC494392
Uncharacterized protein LOC494392.
   
 
 0.576
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.530
H2Y2C6_CIOIN
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.524
LOC100183139
Uncharacterized protein.
    
 
 0.513
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.