STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100185883alanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. (967 aa)    
Predicted Functional Partners:
H2XVW4_CIOIN
AA_TRNA_LIGASE_II_ALA domain-containing protein.
  
  
 
0.906
F6T8P3_CIOIN
Uncharacterized protein.
  
 
 0.901
LOC100178583
Tyrosine--tRNA ligase.
  
 
 0.892
F6SSU2_CIOIN
TPR_REGION domain-containing protein.
   
 0.891
F6ZE60_CIOIN
ANAPC4 domain-containing protein.
   
 0.888
F6UNB7_CIOIN
ANAPC5 domain-containing protein.
   
 0.883
LOC100176838
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
    
 0.877
F6YDG1_CIOIN
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.875
H2XWH9_CIOIN
Protein kinase domain-containing protein.
    
 0.811
H2XL44_CIOIN
AA_TRNA_LIGASE_II domain-containing protein.
 
  
 0.791
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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